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Objectives: The aim of our study was the de- in vitro release kinetics termination of chemical composition and antioxi- using different biorelevant dant activity of indigenous red raspberry leaves Rubi idaei folium.

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Ac- clopidogrel release kinetics evaluation consisted cording to our HPLC results Rubi idaei folium are in the followings: Simulated Gastric Fluid pH an important source of: hyperoside 0.

A set of four biorelevant media, proved in and kaempferol Using HPLC we the literature to be representative for the fasted have also identified rutin, caffeic acid, chlorogen- stomach FaSSGFthe postprandial stomach ic acid and ferulic acid.

The antioxidant octanol mL. Results: Results indicated a highly pH-depen- Conclusions: Red raspberry leaves are an im- dent dissolution profile, with very rapid and com- portant indigenous source of bioactive com- plete dissolution in gastric medium, followed by a pounds that might be used for obtaining several significant tendency to precipitate towards the extracts with antioxidant properties.

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Dissolution in intestinal media was incomplete in both fed and fasting conditions. DPPH and 2,2-azino-bis 3-ethylbenzothiazo- Conclusions: Experiments have led to results linesulfonic acid ABTS and compared with that provide useful information on both the in that of butylated hydroxytoluene BHT and bu- vivo release and absorption of clopidogrel, and tylated hydroxyanisole BHA standards.

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In colani de pre în varicose vector photo complexes 1, 3 and 4, HL1 acts Synthesis, crystal as a mononegative bidentate ligand coordinating to the metal ion through the azomethine nitrogen structure and biological and thiolato sulphur atoms. In complex 2 the li- activity of Cu II complexes gand coordinates in a neutral bidentate manner.

The values of eff 1.

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The Tudor Rosu copper II complexes exhibited better antimicro- University of Medicine and Pharmacy Carol bial and antioxidant activities than those of the Davila, Bucharest, Romania thiocarbohydrazone ligand. Heterocyclic derivatives of thiocarbo- hydrazone are attractive targets of research owing Angela Madalina Lazar1, to their presence in biological, pharmacological Dan Nicolae Straja2, Eugen Bratucu2 and other applications.

Trestioreanu, Bucharest, Romania thiocarbohydrazide. The velops insidiously, with frequent dimensions of thiocarbohydrazone ligand was characterized by more than 20 cm.

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The structures of the cop- ing surgical interventions of curative radical in- per II complexes have been proposed by ele- tent, with negative resection margins. Altogether, mental analyses, molar conductance, spectral IR, surgical radicality remains the only positive prog- UV-Vis and EPRmagnetic and thermal studies. However, currently, there is no consen- mined by single-crystal X-ray diffraction.

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The li- sus between medical centers regarding the prog- gand HL1 and copper II complexes were tested nostic significance of other factors related to the for their antibacterial activity against gram-posi- tumor, patient or colani de pre în varicose vector photo therapeutic nature and dis- tive bacteria Staphylococcus aureus ATCC putes persist even in concern with the degree of and Enterococcus faecalis ATCCgram- aggressiveness required in the case of radical sur- negative bacteria Escherichia coli ATCC gical interventions.

The following ul- over a period of 15 years, on a group of pa- trasound aspect were taken into account and tients with retroperitoneal tumors, operated on in evaluated : average endometrial thickening, en- the First Surgical Clinic of Bucharest Institute of dometrial thickness uniformity, homogeneity and Oncology Prof.

We ana- aspect, dilated glands presence ,disruption of en- lyzed the types of surgical interventions achieved dometrial miometrial line, midline deformation, for this group of patients and their frequency, the doppler aspect, tumor existence with shape as- prognostic differences between various types of pect, hyperechoic line sign and free endometrial non-radical surgical operations.

The average endometrial could be observed, although these have associat- thickness ranged from The histology made.

Pathology is considered gold standard as it is necessary for his- Endometrial polyps, tological anomaly detection. We are interested in researching the ultrasound aspects Introduction: Burn injury represents the most leading to the diagnosis of polyps and comparing severe kind of trauma for the human body.

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The them to the pathology results. There are a lot of ad- Restoring normal ACL vances in burn care, but the treatment of this complex condition requires a multidisciplinary anatomy through burn team that can improve the survival rate and reconstruction using the the quality of life.

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Objectives: This study aims to share our ex- outside-in femoral tunnel perience with multiple burn patients, all victims drilling technique with in a collective accident, an inside fire in Colec- arthroscopic confirmation tiv club. We adhered to the strictest rules of Bogdan Sendrea1, Stefan Mogos2, asepsy and antisepsy from the beginning. Colani de pre în varicose vector photo Femoral tunnel drilling in anterior All the patients were treated with daily wound cruciate ligament ACL reconstruction has been lavage with antiseptic solutions and sterile dress- incriminated for decreased clinical results postop- ings with local antimicrobial agents silver sulfa- eratively.

The objective of the current study was diazineearly necrotic tissue excision and split to evaluate the results of ACL reconstruction us- skin thickness grafting and early rehabilitation. The hypothesis was that this surgical reported internationally. All the patients benefit- technique improves clinical outcomes compared ed of continous professional psychological sup- to the preoperative evaluation. Bronchoscopy and aspiration were per- Methods: The study group included 52 pa- formed regularly in intensive care patients, with tients who underwent ACL reconstruction using tracheostomy for those patients that required the outside-in femoral tunnel drilling technique long-term intubation.

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One patient developed ab- with arthroscopic confirmation of tunnel posi- dominal compartment syndrome that was treated tioning between The group, with laparoscopy surgery. Preoperative and postop- gical specialties were involved in the manage- erative 12 months follow-up clinical parameters ment of these severely burnt patients, but, with the Lachman and pivot shift tests, differential lax- considerable human and material effort, all the ity measurement using the Rolimeter arthrometer, patients survived.

Lysholm Score, IKDC subjective and objective Conclusions: In burn patients, good survival scores, and Tegner activity scale of the group rates and satisfactory rehabilitation perspectives have been recorded and analyzed.

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Postoperatively, 4 pa- tients had positive grade I Lachman test. Pivot shift was grade I positive in 9 patients at follow-up compared to 50 patients pre-operatively. The av- erage Rolimeter differential laxity improved from 6. Mean Lysholm score improved postopera- tively to Postoperative of these were diagnosed prenatal by ultrasound Objective IKDC included 47 patients in groups A examination.